Product Name :
2-Hydroxycinnamaldehyde (CAS 3541-42-2)
Synonym :
3-(2-Hydroxyphenyl)-2-propenal
Application :
CAS:
3541-42-2
Purity:
Molecular Weight:
148.16
Formula :
C9H8O2
Physical state:
Solid
solubility :
Shipping Condition :
Store at room temperature
Melting point:
126° C
SMILES:
C1=CC=C(C(=C1)/C=C/C=O)O
References:
:Constituents of the essential oil of the Cinnamomum cassia stem bark and the biological properties. | Choi, J., et al. 2001. Arch Pharm Res. 24: 418-23. PMID: 11693543Synthesis and biological evaluation of dimeric cinnamaldehydes as potent antitumor agents. | Shin, DS., et al. 2006. Bioorg Med Chem. 14: 2498-506. PMID: 16343908Cinnamaldehydes inhibit thioredoxin reductase and induce Nrf2: potential candidates for cancer therapy and chemoprevention. | Chew, EH., et al. 2010. Free Radic Biol Med. 48: 98-111. PMID: 198371572-Hydroxycurcuminoid induces apoptosis of human tumor cells through the reactive oxygen species-mitochondria pathway. | Han, YM., et al. 2011. Bioorg Med Chem Lett. 21: 747-51. PMID: 21183341Antitumor activity of 2-hydroxycinnamaldehyde for human colon cancer cells through suppression of beta -catenin signaling. | Lee, MA., et al. 2013. J Nat Prod. 76: 1278-84. PMID: 23855266A new coumarin and cytotoxic activities of constituents from Cinnamomum cassia. | Ngoc, TM.56008-63-0 custom synthesis , et al. 2014. Nat Prod Commun. 9: 487-8. PMID: 24868863Diversity-Oriented One-Pot Synthesis to Construct Functionalized Chroman-2-one Derivatives and Other Heterocyclic Compounds.7-Methyl[1,2,3]triazolo[1,5-a]pyridine web | Chen, YH.PMID:33445975 , et al. 2017. J Org Chem. 82: 4774-4783. PMID: 28421761A Bioinspired Cascade Sequence Enables Facile Assembly of Methanodibenzo[b,f][1,5]dioxocin Flavonoid Scaffold. | Liu, H., et al. 2018. Org Lett. 20: 546-549. PMID: 29345470Up-regulation of Bone Morphogenetic Protein 7 by 2-Hydroxycinnamaldehyde Attenuates HNSCC Cell Invasion. | Kang, SM., et al. 2018. Anticancer Res. 38: 5747-5757. PMID: 30275196Synthesis and biological activity of cinnamaldehydes as angiogenesis inhibitors | Byoung-Mog Kwon, Seung-Ho Lee, Young-Kwon Cho, Song-Hae Bok, Seung-Ho So, Mi-Ran Youn, Soo-Ik Chang. 1997. Bioorganic & Medicinal Chemistry Letters. Volume 7, Issue 19: 2473-2476.Antitumor activity of 2-hydroxycinnamaldehyde against human colorectal cancer cells is mediated by the Wnt/ beta -catenin signaling pathway | Won Kyung Kim;, et al. 2014. Cancer Res. 74: 4237.