Product Name :
Stella Rabbit Polyclonal Antibody
Predicted band size :
18 kDa
Observed band size :
25 kDa
Synonyms:
Compaction associated protein 1 antibody Developmental pluripotency associated 3 antibody Developmental pluripotency associated protein 3 antibody Developmental pluripotency-associated protein 3 antibody Dppa3 antibody DPPA3_HUMAN antibody PGC7 antibody Stella related protein antibody Stella-related protein antibody
Function :
Stella is a primordial germ cell (PGCs)-specific protein involved in epigenetic chromatin reprogramming in the zygote following fertilization. It participates in protection of DNA methylation in the maternal pronucleus by preventing conversion of 5mC to 5hmC: specifically recognizes and binds histone H3 dimethylated at ‘Lys-9’ (H3K9me2) on maternal genome, and protects maternal genome from TET3-mediated conversion to 5hmC and subsequent DNA demethylation. It is important for the totipotent/pluripotent states continuing through preimplantation development.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthetic peptide within mouse Stella aa 101-150 / 150 (ID:Q8QZY).
Species reactivity:
Human, Mouse, Zebrafish
Verify application:
WB, IHC-P
Coupling :
unconjugated
Clone number:
RRID:
AB_3073216
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.Formula of 3-DL-Cpa-OH Aliquot store at -20℃ or -80℃.[Ir(dtbbpy)(ppy)2]PF6 Price Avoid repeated freeze / thaw cycles.PMID:33608984
Storage buffer solution:
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 18 kDa
Positive control :
HeLa cell lysate, HEK-293 cell lysate, F9 cell lysate, NCCIT cell lysate, mouse teratoma tissue.