Product Name :
SIGLEC11 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
sialic acid binding Ig like lectin 11 antibody sialic acid binding lectin 11 antibody Sialic acid-binding Ig-like lectin 11 antibody Sialic acid-binding lectin 11 antibody SIG11_HUMAN antibody Siglec 11 antibody Siglec-11 antibody SIGLEC11 antibody
Function :
Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,8-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
KLH conjugated synthetic peptide derived from human SIGLEC11 251-350/698
Species reactivity:
Human
Verify application:
WB, ELISA
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.2-Bromo-N,N-diphenylaniline Chemical name
Storage buffer solution:
0.2-Aminobenzaldehyde Chemscene 01M TBS(pH7.PMID:33682637 4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
74 KDa
Positive control :
Expressed by macrophages in various tissues including Kupffer cells. Also found in brain microglia.